Figure 5
MiR-203 target expression during wound healing. (a) Histological analysis of p63, LASP1, RAN and RAPH1 expression at day 3 after injury. Black bar: 100 μm. Each panel is a composition of six images taken with an × 10 objective to provide high resolution over a wide area, whereas the insets are a magnification ( × 20) of the identified squared boxes: left box, upper inset; right box, lower inset. Black bar in the insets: 20 μm. (b) Cartoon model that summarizes the role of miR-203 and its targets during wound healing. Left panel shows a simplified representation of the wound area, where blue cells indicate differentiated keratinocytes and pink cells proliferating keratinocytes. Right panel shows the inverse correlation between the expression of miR-203 (blue) and its targets (pink)
