Figure 3
From: Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer
Cisplatin induces caspase-8 cleavage in a panel of NSCLC cells but not in H1299 cells. (a) Western blots showing processing of PARP and caspase-8 in a panel of NSCLC cell lines with increasing doses of cisplatin for 24 h. (b) Western blot for caspase-8 in H460 and H1299 sh-BAXBAK cells with matched sh-NTNT controls after 24 h treatment with cisplatin (H460 15 μM, H1299 40 μM)
