Figure 7 | Cell Death & Disease

Figure 7

From: Anthraquinone-2-sulfonic acid (AQ2S) is A Novel Neurotherapeutic Agent

Figure 7

Emodin blocks acute STS-induced AKT activation. Primary rat cortical neurons were seeded onto six-well plates. Neurons were treated with 125 μM AQ2S or 50 μM Emodin+250 nM STS for 6 h. (a) Representative western blots show emodin, but not AQ2S, inhibits AKT activity. (b) Densitometry of western blots (n=4/treatment group). Data was analyzed using one-way-ANOVA (P<0.0001 for all graphs; graphs show mean+S.E.M.). Asterisks indicate significant (P<0.05) results of Fisher LSD post-hoc test

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