Figure 5 | Cell Death & Disease

Figure 5

From: Stabilization of ribozyme-like cis-noncoding rRNAs induces apoptotic and nonapoptotic death in lung cells

Figure 5

Effects on apoptosis and cell cycle at 24 h after single transfection of LNAs. (a) The upper left (UL) and upper right (UR) fractions represent estimated apoptotic cell populations. The lower left (LL) fraction contains nonapoptotic/fragmented cells and the lower right (LR) region corresponds to unaffected cells (X-axis: propidium iodide intensity; Y-axis: fluorescein intensity in log scale). (b) Histogram of cell cycle shows G0/G1, S, and G2/M phases (X-axis: propidium iodide intensity; Y-axis: cell count). The large sub-G0/G1 population in LNA1-S-treated A5 cells is consistent with the marked increase of apoptotic cells in (a). #P<0.05, compared with vehicle; *P<0.05, compared with LNA1-AS

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