Figure 5 | Cell Death & Disease

Figure 5

From: Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts

Figure 5

Mevalonate inhibits simvastatin-induced autophagy, endoplasmic reticulum stress and apoptosis. Myocardial atrial fibroblast were pretreated with mevalonate (2.5 mM, 4 h) and then co-treated with simvastatin (10 μM) for indicated time points. Immunoblots of cell lysates showed inhibition of (a) autophagy, endoplasmic reticulum stress and (b) apoptosis markers

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