Figure 6
From: microRNA-199a-5p protects hepatocytes from bile acid-induced sustained endoplasmic reticulum stress
Ectopic miR-199-5p protects hepatocytes from bile acid-induced ER stress and cell death. HL-7702/L02 (short to L02) cells were transfected with miR-199a-5p mimics or NC with or without SP600125 treatment after culture with TG, DCA, or DMSO for 48 h. (a) Detection of the mRNA ER stress markers GRP78 and CHOP with quantitative RT-PCR. Data are shown as means±S.D. of three independent experiments. **P<0.01. (b) HL-7702/L02 (short to L02) cell death levels were assayed by LDH release. Data are shown as means±S.D. of three independent experiments. **P<0.01
