Figure 5 | Cell Death & Disease

Figure 5

From: Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma

Figure 5

Reduced CTGF activated PI3K/AKT-mediated expression of C-Jun and C-Myc in NPC. (a) Suppressing the expression of PI3K by its specific inhibitor Ly294002 reduced C-Jun and C-Myc expression by inactivating pPI3K/AKT in NPC 6-10B cells. (b) Reduced CTGF stimulated the expression of C-Jun and C-Myc by activating phosphorylated PI3K/AKT, but not their total proteins in NPC 6-10B cells

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