Table 1 Gradual downregulation of CTGF protein in NPC and atypical hyperplasia samples compared with squamous and normal nasopharynx epithelium tissues

From: Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma

Group

Protein expression ( n)

P -value

 

Total

Low

High

S/N/A/C

S/N

A/N

C/N

A/C

S/C

Squamous epithelium

21

3

18

      

Normal epithelium

49

2

47

      

Atypical hyperplasia

37

9

28

      

Cancer

213

124

89

0.000a

0.155b

0.025b

0.000b

0.000b

0.000b

  1. Abbreviations: A, atypical; C, cancer; N, normal; n, patient case; S, squamous.
  2. aKruskal Wallis test
  3. bχ2 test