Figure 2 | Cell Death & Disease

Figure 2

From: Antitumor activity of IL-32β through the activation of lymphocytes, and the inactivation of NF-κB and STAT3 signals

Figure 2

Effect of IL-32β on tumor growth in IL-32β transgenic mice. (a) Tumor images (upper panel), volumes (middle panel), and weights (lower panel) were measured at study termination (on day 24 in transgenic mice (a) as described in Materials and Methods section. The results are expressed as mean±SD from 10 mice; *P<0.05 compared with the nontransgenic mice. (b) tumor sections were analyzed by immunohistochemistry. (c) Tumor extracts were analyzed by western blotting as described in Materials and Methods section. Each images and band are representative of three independent mice. (d) Apoptotic cells were examined by TUNEL staining. (e) Tumor sections were analyzed by immunohistochemistry for detection of IL-32β expression in tumor tissues. Each image is representative of three independent mice. The values on the right or bottom of panels are average fold difference from three independent nontransgenic mice *Significant difference from nontransgenic mice (*P < 0.05)

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