Figure 7 | Cell Death & Disease

Figure 7

From: Eleostearic acid induces RIP1-mediated atypical apoptosis in a kinase-independent manner via ERK phosphorylation, ROS generation and mitochondrial dysfunction

Figure 7

ESA activates Ser/Thr phosphatase calcineurin. (a) Enzymatic activity of calcineurin was measured with or without calmodulin. ESA augmented calcineurin activity regardless of calmodulin. (b) Okadaic acid, a phosphatase inhibitor, significantly reduced ESA-mediated apoptosis. Data were obtained from two independent experiments in triplicates. Values are the means±S.D. *P<0.05 (n=6).

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