Figure 6 | Cell Death & Disease

Figure 6

From: ifn-γ-dependent secretion of IL-10 from Th1 cells and microglia/macrophages contributes to functional recovery after spinal cord injury

Figure 6

Schematic representation showing molecular mechanism of restorative effects of transferred Th1-conditioned lymphocytes on recovery after SCI. ifn-γ-dependent secretion of IL-10 from transferred Th1-conditioned cells contributes to an increase of M2 subtype of MG/MΦs, as shown by the upregulation of IL-10, arginase 1 (Arg1), and CD206, leading to restorative effects on functional recovery after SCI

Back to article page