Figure 5 | Cell Death & Disease

Figure 5

From: KPNA2 promotes cell proliferation and tumorigenicity in epithelial ovarian carcinoma through upregulation of c-Myc and downregulation of FOXO3a

Figure 5

Depletion of KPNA2 induces G1/S arrest of EOC cells (by real-time qRT-PCR analysis). (a and b) Relative mRNA expression of KPNA2, cyclin D1, ki-67, p21Cip1, and p27Kip1 in the indicated EOC cells was determined by real-time qRT-PCR. Expression levels were normalized to β-actin. (c and d) Western blotting analysis of KPNA2, cyclin D1, ki-67, p21Cip1, and p27Kip1 proteins (top) in the indicated EOC cells. (e and f) Expression levels were quantitated using ImageJ software (Wayne Rashband; bottom); β-actin was used as a loading control. Error bars represent the S.D. of three independent experiments

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