Table 2 Univariate and multivariate analysis of factors associated with overall survival

From: KPNA2 promotes cell proliferation and tumorigenicity in epithelial ovarian carcinoma through upregulation of c-Myc and downregulation of FOXO3a

Clinical variable

Subset

Hazard ratio (95% CI)

P -value

Univariate analysis

 Histology

Others versus mucinous versus serious

0.672 (0.426–1.058)

0.086

 FIGO stage

III/IV versus I/II

3.905 (2.439–6.252)

<0.001

 Differentiation

Poor versus moderate versus well

1.701 (1.326–2.181)

<0.001

 Cytoreductive surgery

Suboptimal cytoreduction versus optimal cytoreduction

3.302 (2.032–5.364)

<0.001

 Expression of KPNA2

High versus low

2.404 (1.563–3.697)

<0.001

Multivariate analysis

 FIGO stage

III/IV versus I/II

3.570 (1.984–6.424)

<0.001

 Cytoreductive surgery

Suboptimal cytoreduction versus optimal cytoreduction

1.819 (1.096–3.018)

0.021

 Expression of KPNA2

High versus low

1.832 (1.137–2.951)

0.013

  1. Abbreviations: CI, confidence interval; FIGO, International Federation of Gynecology and Obstetrics.
  2. Bold P-values indicate significance (P<0.05)