Figure 4 | Cell Death & Disease

Figure 4

From: Differential effect of long-term drug selection with doxorubicin and vorinostat on neuroblastoma cells with cancer stem cell characteristics

Figure 4

BD Biocoat Matrigel in vitro invasion assay was used to compare the WT, WT-v, DoxR, and DoxR-v (a) SK-N-Be(2)C and (b) SK-N-SH cell lines. Invasion was calculated as the percentage of cells able to invade through a membrane coated with a defined matrix (collagen IV, laminin, and gelatin) during a 24-h period as a fraction of the control inserts. Bars represent the normalized invasion indices. Error bar=95% confidence interval. *P=0.01, **P=0.02, ***P=0.004, ****P<0.001. Experiments were repeated at least five times

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