Figure 6
From: Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death
BIX01294 does not interfere with the uptake of the gentamicin and FM1-43FX. (a and b) Explants were incubated with GTTR for 30 min in the absence or presence of BIX01294. The red fluorescence represents GTTR, the green fluorescence represents the hair cells, and blue represents DAPI (4,6-diamidino-2-phenylindole) staining of the nuclei. Shown here are the confocal images of the middle segments of each group. Bar=20 μm. (c and d) The hair cell function was not affected when measuring the uptake of FM1-43FX in the presence or absence of 2 μM BIX01294. GFP, green fluorescent protein
