Figure 3 | Cell Death & Disease

Figure 3

From: Interdigital cell death in the embryonic limb is associated with depletion of Reelin in the extracellular matrix

Figure 3

(a–c) Detailed view of reelin expression at 5.5 i.d., 6 h after interdigital implantation of PBS/BSA-soaked beads (a), FGF2-soaked beads (b), and BMP7-soaked beads (c). Note the upregulation of reelin expression in (b) and the downregulation in (c) in comparison to the control (a). Implanted bead is indicated by (*). (b′) QPCR plot showing the positive regulation of reelin in samples of the third interdigit isolated from the autopod 10 h after FGF-bead implantation. (c′) QPCR plots showing reelin downregulation in interdigit explants treated with BMP-7. **P<0.01; *P<0.05

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