Figure 1

The synergistic effects of RXN (180 mg/kg), which contains GbE (80 mg/kg) and CS (100 mg/kg), against CDDP (16 mg/kg)-induced hearing loss. (a) Hearing threshold (dB) at 16 kHz and 32 kHz before (Pre) and after (post-5 day) CDDP administration. (b) OHC, number of hair cells counted in the middle and basal turns of the Organ of the Corti. *P<0.05, **P<0.01. Asterisk on the bar means compared with the normal control group. (c) Scanning electron micrographs of hair cells in different groups. Scale bars=10 μm