Figure 3 | Cell Death & Disease

Figure 3

From: The HDAC inhibitor, MPT0E028, enhances erlotinib-induced cell death in EGFR-TKI-resistant NSCLC cells

Figure 3

Assessment of apoptosis by propidium iodide in A549 cells. (a) Induction of apoptosis (subG1 phase) in A549 cells treated with MPT0E028 (M) in combination with erlotinib (E). Cells were treated with the indicated concentrations (μM) for 72 h, stained with propidium iodide, and assessed by flow cytometry. (b and c) The percentage of cells in sub-G1 at 72 h after treatment with erlotinib/MPT0E028 (b) or erlotinib/SAHA (c). Data are representative of the results from at least three independent experiments. Error bars represent S.D.

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