Figure 1 | Cell Death & Disease

Figure 1

From: Suppression of polyglutamine protein toxicity by co-expression of a heat-shock protein 40 and a heat-shock protein 110

Figure 1

DNAJ-1 suppresses polyQ-induced degeneration independently of HSP70. (a–c) Photographs of the external eye of (a) wild-type, (a’) Df(3R)hsp70, (b) GMR>127Q: GMR-Gal4 UAS-127Q/+, (b’) GMR>127Q;Df(3R)hsp70: GMR-Gal4 UAS-127Q/+;Df(3R)hsp70, (c) GMR>127Q dnaJ-1: GMR-Gal4 UAS-127Q UAS-dnaJ-1/+, (c’)GMR>127Q dnaJ-1;Df(3R)hsp70: GMR-Gal4 UAS-127Q UAS-dnaJ-1/+;Df(3R)hsp70. Scale bar on (a) represents 100 μm. (d–g) Examination of retinal morphology by TEM. Cross-sections were obtained from flies under 1-day old. (d) wild-type, (e) GMR>127Q, (f) GMR>127Q dnaJ-1, (g) GMR>127Q dnaJ-1;Df(3 R)hsp70. The scale bar in d represents 5 μm, (h) Histogram of the mean number of rhabdomeres per ommatidium

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