Figure 4

PDCD4 mediated cell apoptosis in NPC. (a) Restoration of PDCD4 expression induced the cleavage of CASP9, 3, 6, 7 and PARP and suppressed BCL2 expression. (b) Stably knocking down the expression of PDCD4 by shRNA reduced the cleavage of CASP9, 3, 6, 7 and PARP and elevated the expression of BCL2