Figure 1 | Cell Death & Disease

Figure 1

From: Zinc chelation: a metallothionein 2A’s mechanism of action involved in osteosarcoma cell death and chemotherapy resistance

Figure 1

Atorvastatin increases MT2A expression in osteosarcoma cells. SaOS2 and U2OS cells were incubated in the presence or absence of atorvastatin (10 μM) for 24 h. (a) MT2A mRNA levels were evaluated by RT-qPCR. (b) MT2A and housekeeping gene β-actin protein levels were assessed by western blot analysis. (c) Free intracellular zinc content was evaluated by fluorimetry. Results are expressed as mean±S.D. *P<0.05 versus untreated cells

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