Figure 4
From: Implication of transcriptional repression in compound C-induced apoptosis in cancer cells

The induction of p53 is not involved in compound C-induced apoptosis. (a) A549 and SMMC-7721 cells were treated with 10 μmol/l compound C for indicated periods with or without PFT-α (20 μmol/l) pretreatment for 1 h and cell lysates were analyzed for the levels of indicated proteins. (b) After GFP or P53 siRNAs transient transfection for 48 h, A549 and SMMC-7721 cells were treated with 10 μmol/l compound C for indicated periods and cell lysates were analyzed for the levels of indicated proteins