Figure 7

AF-induced phenotype changes in CD4⁺ T cells from HIV-infected individuals. Shown are the proportions of CD4⁺ T-cell subpopulations of human HIV⁺ subjects, under ART, after 2 days of treatment with auranofin. CD4⁺ T-naive (T_N; i.e., CD45RA⁺ CD27⁺ CCR7⁺), CD4⁺ T-central memory (T_CM; CD45RA⁻ CD27⁺ CCR7⁺), CD4⁺ T-transitional memory (T_TM; CD45RA⁻ CD27⁺ CCR7⁻) and CD4⁺ T-effector memory (T_EM; CD45RA⁻ CD27⁻ CCR7⁻), CCR7⁺ CD27⁻. The P-values are shown, as obtained by paired t-test analysis following a LOGIT transformation to restore normality