Figure 3 | Cell Death & Disease

Figure 3

From: Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells, and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway

Figure 3

WA induces cell-cycle arrest in NCI-H460 and NCI-H446 cells. (a) Cells were treated with or without 10 μM WA for the indicated time periods and then the cell-cycle distribution was measured using flow cytometry. The percentage of cells in each population was shown as mean±S.D. from three independent experiments. *P<0.05, **P<0.01. (b) Western blot analysis of G2/M transition-related proteins after WA treatment

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