Figure 5 | Cell Death & Disease

Figure 5

From: The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expression

Figure 5

Roc-A does not protect cancer cell lines with nonfunctional p53. p53-mutated or -deficient cancer cell lines (a) and p53 WT cell lines (b) were treated with solvent (DMSO) or different concentrations of Etoposide in the presence of increasing amounts of Roc-A or solvent (DMSO) as indicated. Cell death was determined by DNA fragmentation after 24 or 48 h of treatment as indicated. Results are averages of three independent experiments. Error bars (S.D.) are shown

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