Figure 2
From: MiR-216a: a link between endothelial dysfunction and autophagy
miR-216a and autophagy-related genes in atherosclerosis and heart failure. (a) Expression of miR-216a in unstable compared with stable plaques (n=10 per group) (*P=0.02. Student’s t-test, data are mean ± S.E.M.). (b) Correlation between miR-216a and BECN1 and ATG5 mRNA expression in human atherosclerotic plaques (n=65) (Spearman’s correlation test). (c) miR-216a expression in patients divided upon circulating LDL tertiles (LSD post-hoc analysis) D, BECN1 and ATG5 mRNA expression in myocardial biopsies from heart failure (HF) patients (n=13) compared with normal subjects (n=12) (*P<0.05, **P<0.01.Student’s t test, data are mean ± S.E.M.). (e) Correlation between miR-216a and BECN1 and ATG5 mRNA expression in myocardial biopsies (n=25) (Spearman’s correlation test)
