Figure 3
From: Zebularine regulates early stages of mESC differentiation: effect on cardiac commitment
Effects of chronotropic drugs in zebularine-treated cells. (a) Median of beating frequency in samples 1 and 2 min after treatment with 2 μM isoproterenol. Results are means±S.D. for 50 different areas from three experiments. ***A statistically significant difference of isoproterenol administration compared with zebularine (paired Student’s t-test; P<0.001). (b) Contraction frequency registration of nine contractile areas from three different experiments showing that 2 μM isoproterenol increased beating frequency and 50 μM diltiazem was able to stop contractions 71.6 s after administration
