Figure 2
FGFR4 is differentially expressed in human colon adenocarcinoma versus normal colonic mucosal tissue. (a) FGFR4 transcriptional profiling in the Oncomine database. The Oncomine database of publicly available microarray data was searched for differential expression of FGFR4 between normal colon and colonic adenocarcinoma tissue. The bar graphs and box plots are shown for each data set as well as the sample breakdown, reference, platform used, fold change and level of significance as determined by the Student’s t-test. (b) Representative high-powered ( × 40) images illustrating weak nuclear staining for FGFR4 in normal colon and strong nuclear staining in colonic adenocarcinomas. Bar graph representing the relative immunoreactivity score calculated for FGFR4 nuclear staining in normal and malignant colorectal epithelial cells
