Figure 6
From: ATP/P2X7 axis modulates myeloid-derived suppressor cell functions in neuroblastoma microenvironment
MSC-1 and MSC-2 express a functional P2X7R. Panel a and b show the expression of P2X7R mRNA and protein in MSC-1 and MSC-2 lines (positive controls: N9 microglia and J774 macrophages). Panels c–f show [Ca2+)]i increases and BzATP dose dependency in MSC-1 (c and d) and MSC-2 (Panels e and f) lines. Panels g–j show EtBr uptake and BzATP dose dependency in MSC-1 (g and h) and MSC-2 (i and j) lines
