Table 1 Cytokines and chemokines secreted by G-MDSCs and M-MDSCs isolated from TF and NB-bearing mice
From: ATP/P2X7 axis modulates myeloid-derived suppressor cell functions in neuroblastoma microenvironment
TF G-MDSCs | TF M-MDSCs | NB G-MDSCs | NB M-MDSCs | |
|---|---|---|---|---|
IL-1 α | 1±0.18 | 1.18±0.18 | 0.7±0.1 | 1±0.12 |
IL-1 β | 67±1.4 | 76.8±1.5 | 84±3 | 102±11 |
IL-2 | 6±0.8 | 6.3±0.8 | 4.8±0.5 | 6.5±0.6 |
IL-3 | 0.23±0.01 | 0.24±0.01 | 0.23±0.01 | 0.22±0.01 |
IL-4 | – | – | – | – |
IL-5 | 0.54±0.03 | 0.64±0.1 | 0.3±0.01 | – |
IL-6 | – | – | – | – |
IL-9 | – | – | – | – |
IL-10 | 4.1±0.2 | 4.4±0.4 | 3±0.7 | 3.9±0.3 |
IL-12 (p40) | – | – | – | – |
IL-12 (p70) | 4.6±0.2 | 5.5±0.7 | 5.4±1.2 | 6±1.5 |
IL-13 | 8±1.5 | 10.3±0.75 | – | 9.2±1.2 |
IL-17 | – | – | – | – |
Eotaxin (CCL11) | 24±3.4 | 23.3±4.2 | 13.7±5 | 18±0.5 |
G-CSF | – | – | – | – |
GM-CSF | – | – | – | – |
IFN-γ | 0.5±0.3 | 0.4±0.03 | 0.54±0.05 | 0.46±0.03 |
KC (CXCL1) | – | – | – | – |
MCP-1 (CCL2) | 25.5±0.4 | 24.2±0.8 | 17.4±1.8 | 16.5±0.6 |
MIP-1 α (CCL3) | 1.7±0.2 | 2.5±0.2 | 0.35±0.1 | 1.8±0.6 |
MIP-1 β (CLL4) | 1.9±0.6 | 2.5±1 | 1.3±0.3 | 2.9±0.7 |
RANTES (CLL5) | 0.8±0.05 | 0.66±0.03 | 0.1±0.06 | 0.5±0.09 |
TNF-α | 7.8±0.8 | 7.9±0.8 | 6.3±0.7 | 6.4±1.3 |
