Figure 2 | Cell Death & Disease

Figure 2

From: Temozolomide resistance in glioblastoma cells occurs partly through epidermal growth factor receptor-mediated induction of connexin 43

Figure 2

Cell viability of TMZ-treated Cx43 knockdown GBM cells. U87 and T98G were transfected with Cx43-targeted siRNA or a non-targeting siRNA (Negative Control, Neg Ctrl). The cells were analyzed by real-time PCR for Cx43 mRNA (a) and whole-cell extracts in western blot with anti-Cx43 (b). The knockdown cells, Neg Ctrl and untransfected cells were treated with 200 μM TMZ. After 72 h, the cells were studied for viability using the CytoTox 96 LDH release. The results are presented as mean±S.D. of triplicates from each of four independent experiments (n=12).*P<0.05 versus Neg Ctrl and untransfected cells

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