Figure 4 | Cell Death & Disease

Figure 4

From: Arginine vasopressin neuronal loss results from autophagy-associated cell death in a mouse model for familial neurohypophysial diabetes insipidus

Figure 4

Autophagosome formation and p62 expression in AVP neurons of FNDI/GFP-LC3 mice. (a) Immunofluorescence staining for GFP (green) and mutant NPII (magenta) in the SON of 3-month-old FNDI/GFP-LC3 mice with water access ad libitum (ad lib) and of those subjected to WD for 4 weeks (WD4). (b) Immunofluorescence staining for p62 (magenta) and NPII (green) in the SON of 3-month-old FNDI mice in ad lib and WD4 groups. (c) Immunofluorescence staining for p62 (magenta) and GFP-LC3 (green) in the SON of 3-month-old FNDI/GFP-LC3 mice in WD4 group. Scale bars, 10 μm (a and b), 5 μm (c)

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