Figure 8 | Cell Death & Disease

Figure 8

From: Arginine vasopressin neuronal loss results from autophagy-associated cell death in a mouse model for familial neurohypophysial diabetes insipidus

Figure 8

Possible mechanisms of cell death of AVP neurons in FNDI mice. Aggregates are confined to a sub-compartment of the ER, so-called ERAC, in AVP neurons of the SON in FNDI mice. Failure of ERAC formation leads to autophagy. When autophagy continues, the organelles including ER are lost over time, leading to autophagy-associated cell death

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