Figure 6
From: Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer

Effect of downregulation of Jagged1 by L-Jagged1-shRNA on the growth of xenograft tumors in nude mice. Mice (n=8) were s.c. injected into the flanks with HCT15 cells stably infected with L-Jagged1-shRNA (left) or scrambled-shRNA (right). Tumor volumes were measured once every 3 days and tumor tissues were harvested 31 days after cell injection. The tumor growth curve was shown (a). The average tumor weight (n=8) was measured after the mice were harvested (b). Representative tumor-bearing mice (c) and the harvested xenograft tumor tissues (d) are shown. *P<0.05