Figure 2 | Cell Death & Disease

Figure 2

From: Mesenchymal stem cells infected with Mycoplasma arginini secrete complement C3 to regulate immunoglobulin production in b lymphocytes

Figure 2

CM harvested from mycoplasma-free MSCs did not inhibit IgE production in B cells. (a) In addition to IgE, production of other Ig isotypes including IgM and IgG1 was also decreased by mycoplasma-contaminated MSC-CM in LPS/IL-4-stimulated B cells. However, Ig production (IgE, IgG1, and IgM) was not observed when mycoplasma-free MSC-CM was added. (b) Mycoplasma infection was determined by PCR. myco(+), CM from mycoplasma-infected MSCs; myco(−), CM from mycoplasma-free MSCs

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