Figure 1 | Cell Death & Disease

Figure 1

From: P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression

Figure 1

Analysis of TUG1 expression in NSCLC tissues and clinical parameters. (a) TUG1 was detected in 192 pairs of NSCLC tissues by qRT-PCR. The levels of TUG1 in NSCLC tissues are significantly lower than those in non-tumorous tissues. The ΔCt value was determined by subtracting the GAPDH Ct value from the TUG1 Ct value (relative to a single reference value). Smaller ΔCt value indicates higher expression. (b and c) Data are presented as relative expression level in tumor tissues (shown as ΔCt). TUG1 expression was significantly lower in patients with a higher pathological stage and big tumor size. (d) Patients with low levels of TUG1 expression showed reduced survival times compared with patients with high levels of TUG1 expression (P<0.001, log-rank test). **P<0.01

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