Figure 4 | Cell Death & Disease

Figure 4

From: P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression

Figure 4

The impact of TUG1 on tumorigenesis in vivo. (a and b) Scramble or shTUG1 was transfected into SPC-A1 cells, which were injected in the nude mice (n=10), respectively. Tumor volumes were calculated after injection every 2 days. Bars indicate S.D. (c) Tumor weights are represented as means of tumor weights ±S.D. qRT-PCR was performed to detect the average expression of TUG1. (d) Histopathology of xenograft tumors. The tumor sections were under H&E staining and IHC staining using antibodies against Ki-67. Bar, 100 μm. Error bars indicate means±S.E.M. *P<0.05, **P<0.01

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