Table 1 Proteomics data, ranked by fold change for 10 differentially expressed (at least twofold) characterised protein between control and IR
From: Radiation induces senescence and a bystander effect through metabolic alterations
Spot number | Fold change | Protein name/NCBI accession/gene name (Homo sapiens) | Function |
|---|---|---|---|
3207 | +9.8 | Proteasome activator complex subunit 3 isoform 2, NCBI accession no. 30410796, PSME3 | Peptide cleavage |
7201 | +6.63 | Glyceraldehyde-3-phosphate dehydrogenase, NCBI accession no. 31645, GAPDH | Metabolism |
7409 | +4.64 | 26S Protease regulatory subunit 8 isoform 2, NCBI accession no. 312596881, PSMC5 | Peptide cleavage |
2608 | +4.45 | Copine-1 isoform a, NCBI accession no. 23397696, CPNE1 | Membrane trafficking |
7508 | +4.06 | Adenylyl cyclase-associated protein 1, NCBI accession no. 5453595, CAP1 | Metabolism/motility |
2811 | +3.65 | Heat-shock protein 105 kDa, NCBI accession no. 42544159, HSPH1 | Protein folding |
1216 | +3.28 | Chain A, the effect of metal binding on the structure of annexin V and implications for membrane binding, NCBI accession no. 809185, ANXA5 | Membrane trafficking |
2805 | +3.13 | Transitional endoplasmic reticulum ATPase, NCBI accession no. 6005942, VCP | Transport/Protein degradation |
4417 | −23.92 | Adenosylhomocysteinase isoform 1, NCBI accession no. 9951915, AHCY | Methylation |
5414 | −30.59 | 26S Proteasome subunit 9, NCBI accession no. 2150046, PSMD9 | Peptide cleavage |
