Figure 2 | Cell Death & Disease

Figure 2

From: EGF-induced adipose tissue mesothelial cells undergo functional vascular smooth muscle differentiation

Figure 2

Efficient transdifferentiation of ATMCs towards VSM-like cells through subsequent subculture into BMe+50EGF. (a) Schematic representation of the stepwise protocol used to direct ATMCs towards VSM-like cells. (b) Immunofluorescence characterization of ATMCs transdifferentiation towards VSM-like cells. Left images show representative phase contrast pictures of ATMCs cultured for 1, 3, 5, 10 and 15 days in BMe+50EGF. Left to right, shows corresponding immunofluorescence expression patterns against epithelial (β-catenin and CK19), mesothelial (WT1) and VSMCs (α-SMA and Smtn-B) markers

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