Figure 7 | Cell Death & Disease

Figure 7

From: FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway

Figure 7

FZD7 downregulation inhibits RhoA but activates Rac1 activity. (a) G-LISA RhoA and (b) Rac1 expression after FZD7 downregulation in CH1, PA-1 and OV-17R cell lines. (c) Graph shows cell polarity (in μM) (z axis) after knockdown with FZD7 siRNA. (d) Graph shows the results of the wound healing assay after knockdown of FZD7. P-value *<0.05, **<0.01 and ***<0.001

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