Figure 2 | Cell Death & Disease

Figure 2

From: Direct optic nerve sheath (DONS) application of Schwann cells prolongs retinal ganglion cell survival in vivo

Figure 2

SC/DONS application of SCs reduces in vivo RGC apoptosis. RGC apoptosis was labelled by intravitreal injection of fluorescently-labelled annexin V and imaged using a cSLO. Representative DARC images show RGC apoptosis (white spots) at baseline (a and b), pONT only (c and d), and SC/DONS-treated pONT (pONT+SC/DONS, e and f) at 7 (a, c, e), and 21 (b, d, f) days following treatment. pONT induced a significant increase of RGC apoptosis at 7 and 21 days, compared with normal control (g) and SC/DONS treatment significantly reduced RGC apoptosis at both 7 and 21 days compared with untreated group (pONT) (g and h). Data were presented as means±S.E. *P<0.05, **P<0.01

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