Figure 7
From: TRAF1 is a key mediator for hepatic ischemia/reperfusion injury
TRAF1 has an important role in the activation of the ASK1-MKK4–JNK signaling pathway. (a, b) Western blot analysis (left) and quantification (right) of the levels of the indicated proteins in the hepatic tissues of WT/TRAF1 KO (a) and NTG/TRAF1 TG (b) mice after sham surgery or 12 h liver I/R (n=6, *P<0.05 versus sham, #P<0.05 versus I/R). (c, d) Western blot analysis (left) and quantification (right) of the levels of the indicated proteins in hepatocytes infected with the indicated adenovirus for 48 h and subjected to H/R for 6 h (n=6, *P<0.05 versus AdshRNA or AdGFP control, #P<0.05 versus AdshRNA or AdGFP H/R). GAPDH served as an internal control. Data are presented as the mean±S.D.
