Figure 4 | Cell Death & Disease

Figure 4

From: Nanoencapsulation of ABT-737 and camptothecin enhances their clinical potential through synergistic antitumor effects and reduction of systemic toxicity

Figure 4

Synergistic effects of free ABT-737 and CPT on colorectal cancer cells. (a) Affected (non-viable) cell fractions following treatment of HCT116 cells with ABT-737, CPT and both drugs in combination for 48 h assessed by MTT cell viability assay, mean±S.E.M., n=3. (b) Combination indices calculated from cell viability data in (a), mean±S.E.M., n=3. (c) Effect of drug combinations on PARP cleavage in HCT116 cells after 24 h incubation

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