Table 1 Categorized functions of caspases
Cellular events | Caspases | References |
---|---|---|
Apoptosis | Caspase-2, -3, -6, -7, -8, -9 and -10 | |
Inflammation | Human: caspase-1, -4, -5 and -12; Mouse: caspase-1, -11 and -12 | |
Pyroptosis | Caspase-1 and -11 | |
Necroptosis | Caspase-8 as negative regulator | |
Proliferation | Caspase-6 and -8 | |
Unspecified | Caspase-2, -10 and -14 |