Table 1 Categorized functions of caspases

From: Revisiting caspases in sepsis

Cellular events

Caspases

References

Apoptosis

Caspase-2, -3, -6, -7, -8, -9 and -10

11

Inflammation

Human: caspase-1, -4, -5 and -12; Mouse: caspase-1, -11 and -12

12, 20

Pyroptosis

Caspase-1 and -11

12, 13, 14

Necroptosis

Caspase-8 as negative regulator

16, 53

Proliferation

Caspase-6 and -8

22, 23, 24, 25, 26

Unspecified

Caspase-2, -10 and -14

90