Table 1 Biological processes most enriched in the analyzed genes

From: Analysis of gene expression array in TSC2-deficient AML cells reveals IRF7 as a pivotal factor in the Rheb/mTOR pathway

Term

Count

%

P -value

GO:0009615 – response to virus

10

2.53

0.0009

GO:0010941 – regulation of cell death

34

8.61

0.0010

GO:0048518 – positive regulation of biological process

68

17.22

0.0010

GO:0006793 – phosphorus metabolic process

38

9.62

0.0016

GO:0006952 – defense response

27

6.84

0.0019

GO:0009611 – response to wounding

24

6.08

0.0025

GO:0048002 – antigen processing and antigen peptide presentation

5

1.27

0.0036

GO:0048522 – positive regulation of cellular process

60

15.19

0.0044

GO:0045087 – innate immune response

10

2.53

0.0045

GO:0051270 – regulation of cell motion

12

3.04

0.0049

GO:0019538 – protein metabolic process

84

21.27

0.0060

GO:0032879 – regulation of localization

25

6.33

0.0071

GO:0051272 – positive regulation of cell motion

8

2.03

0.0072

GO:0043069 – negative regulation of programmed cell death

17

4.30

0.0085

GO:0060548 – negative regulation of cell death

17

4.30

0.0088

GO:0040012 – regulation of locomotion

11

2.78

0.0129

GO:0030334 – regulation of cell migration

10

2.53

0.0158

GO:0051707 – response to other organism

14

3.54

0.0162

GO:0040017 – positive regulation of locomotion

7

1.77

0.0249

GO:0006897 – endocytosis

11

2.78

0.0300

GO:0010324 – membrane invagination

11

2.78

0.0300

GO:0006935 – chemotaxis

9

2.28

0.0308

GO:0042330 – taxis

9

2.28

0.0308

GO:0002682 – regulation of immune system process

16

4.05

0.0318

GO:0006082 – organic acid metabolic process

21

5.32

0.0330

GO:0001666 – response to hypoxia

8

2.03

0.0343

GO:0042180 – cellular ketone metabolic process

21

5.32

0.0363

GO:0042127 – regulation of cell proliferation

27

6.84

0.0381

GO:0010942 – positive regulation of cell death

17

4.30

0.0423

GO:0070482 – response to oxygen levels

8

2.03

0.0433

GO:0044093 – positive regulation of molecular function

21

5.32

0.0487

  1. Ease score<0.05