Figure 1 | Cell Death & Disease

Figure 1

From: APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation

Figure 1

AICD is recruited to the miRNA-embedding regions in SH-SY5Y cells. (a and b) Distribution of AICD miRNA-binding peaks from the first (a) and second (b) ChIP-seq data sets in exons, introns, 3’-UTR, transcription terminal site (TTS), promoter-transcription start site (TSS) and intergenic regions of the genome. (c) Overlap of the miRNAs indicated by AICD-binding peaks from the first and second ChIP-seq data sets. (d and e) The distribution of the peaks within 200 kb (d) and 10 kb (e) of miRNA SSS. The x axis shows the base distance from the miRNA SSS, noted as 0. The y axis is the number of peaks counted in the regions. (f) Functional annotation clustering analysis of the AICD ChIP miRNAs and schematic diagram of the strategy of this study

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