Table 1 Top molecular pathways deregulated in shNFAT1 knocked down cells

From: The calcineurin/NFAT pathway is activated in diagnostic breast cancer cases and is essential to survival and metastasis of mammary cancer cells

Molecular and cell function

Significance

Cellular movement

3.00 × 10−8

Cell death and survival

1.94 × 10−7

Cellular development

2.88 × 10−7

Cellular growth and proliferation

2.88 × 10−7

Cellular function and maintenance

3.47 × 10−5

  1. The 325 genes that showed an at least twofold expression change between control and shNFAT1 samples were submitted to pathway analysis using the Ingenuity Pathways Analysis (IPA).
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