Figure 4
From: APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells
MQ is the active moiety of APR-246. (a) Effect of APR-246, MQ, APR-320 and MQ-H on viability of ovarian cancer A2780-CP20 cells. The WST-1 assay was used for measurement of cell viability. The results are shown as mean±S.E.M. (n=2). (b) Synergistic effects of MQ and cisplatin on cell viability of A2780-CP20 cells. FMCA was used for measurement of cell viability and Additive model for analysis of results. CI values are presented above the bars. CI<0.8 indicates synergistic and <0.5 strong synergistic effects. CI values <0.8 are marked in red. Results are shown as mean±S.E.M. (n=3)
