Figure 1 | Cell Death & Disease

Figure 1

From: 1α, 25-Dihydroxyvitamin D3 and the vitamin D receptor regulates ΔNp63α levels and keratinocyte proliferation

Figure 1

VDR is essential for basal expression of ΔNp63α. (a) HaCaT (left panel), HaCaT II-4 (right panel) and (b) neonatal human epidermal keratinocyte cells were transfected with non-silencing control (NSC) or siRNA against VDR. The change in mRNA levels and protein expression of p63 and VDR were measured by qRT-PCR (*P values≤0.05) and immunoblot analyses, respectively. (c) The change in transcript levels of p63 and VDR were measured by qRT-PCR in total RNA extracted from skin of wild-type or VDR knockout (KO) mice. *P values≤0.05

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