Table 1 Gene array analysis

Gene expression elevated in TAM67-negative epidermis

Cutaneous keratins

−4.08

Krt71

Keratin 71

−3.64

Krt25

Keratin 25

−3.47

Krt27

Keratin 27

−3.47

Krt26

Keratin 26

−3.04

Krt15

Keratin 15

−3.02

Krt28

Keratin 28

−2.88

Krt72

Keratin 72

−2.41

Krt77

Keratin 77

−2.37

Krt73

Keratin 73

−2.32

Krt23

Keratin 23

−2.13

Krt78

Keratin 78

Hair keratins and associated proteins

−3.66

Krt33a

Keratin 33a

−3.19

Krt86

Keratin 86

−2.47

Krt31

Keratin 31

−4.43

Krtap7-1

Keratin associated protein 7-1

−4.39

Krtap8-1

Keratin associated protein 8-1

−3.46

Krtap3-3

Keratin associated protein 3-3

−3.27

Krtap1-5

Keratin associated protein 1-5

−3.04

Krtap6-1

Keratin associated protein 6-1

−3.03

Krtap16-8

Keratin associated protein 16-8

−2.92

Krtap4-16

Keratin associated protein 4-16

−2.91

Krtap4-1

Keratin associated protein 4-1

−2.77

Krtap8-2

Keratin associated protein 8-2

−2.67

Krtap13-1

Keratin associated protein 13-1

−2.64

Krtap6-3

Keratin associated protein 6-3

−2.57

Krtap4-7

Keratin associated protein 4-7

−2.23

Krtap1-4

Keratin associated protein 1-4

−2.03

Krtap4-2

Keratin associated protein 4-2

−1.83

Krtap3-1

Keratin associated protein 3-1

−1.83

Krtap16-7

Keratin associated protein 16-7

−1.80

Krtap3-2

Keratin associated protein 3-2

−1.77

Krtap1-3

Keratin associated protein 1-3

−1.70

Krtap16-5

Keratin associated protein 16-5

Early envelope

−1.8

Sprr4

Small protein-rich protein 4

Late envelope

−3.97

Lce1m

Late cornified envelope 1M

−3.83

Lce1d

Late cornified envelope 1D

−3.79

Lce1a2

Late cornified envelope 1A2

−3.73

Lce6a

Late cornified envelope 6A

−3.56

Lce1f

Late cornified envelope 1F

−3.51

Lce1e

Late cornified envelope 1E

−3.40

Lce1b

Late cornified envelope 1B

−3.37

Kprp

Keratinocyte proline-rich protein

−3.23

Lce1l

Late cornified envelope 1L

−2.79

Lce1c

Late cornified envelope 1C

−2.48

Lce1a1

Late cornified envelope 1A1

−2.29

Lce1h

Late cornified envelope 1H

−2.16

Lce1j

Late cornified envelope 1J

−2.16

Lce1g

Late cornified envelope 1G

−2.67

Lor

Loricrin

Filaggrin-related proteins

−5.55

Flg2

Filaggrin2

−3.53

Tchh

Trichohyalin

−2.26

Crnn

Cornulin

Proteases and protease inhibitors

−3.68

Tmprss11f

Transmembrane protease, serine 11f

−3.02

Serpina12

Serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12

Lipoxygenases

−3.67

Alox12e

Arachidonate lipoxygenase, epidermal

Gene expression elevated in TAM67-positive epidermis

Cutaneous keratins

+1.75

Krt6a

Keratin 6a

+1.68

Krt16

Keratin 16

+1.60

Krt17

Keratin 17

Early envelope

+2.40

Sprr2b

Small proline-rich protein 2B

+2.14

Tgm3

Transglutaminase type III

+2.00

Sprr2d

Small proline-rich protein 2D

+1.62

Sprr2e

Small proline-rich protein 2E

Proteases and protease inhibitors

+4.19

Serpinb3a

Serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A

+2.51

Serpinb3d

Serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D

+1.80

Serpinb6c

Serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 6C

+2.07

Spink12

Serine peptidase inhibitor, Kazal type 12

+2.04

Klk13

Kallikrein related-peptidase 13

+1.89

Serpinb2

Plasminogen activator inhibitor 2

+1.84

Capn2

Calpain 2

Envelope defense

+3.82

S100a8

S100A8

+3.72

Defb3

Defensin beta 3

+3.19

S100a9

S100A9

+2.00

Defb4

Defensin beta 4

Chitinase-like proteins

+4.18

Chi3l4

Chitinase-3-like protein 3

Desmosome

+1.99

Dsc2

Desmocollin 2

+1.91

Dsg3

Desmoglein 3